Enhancer blocking by the Drosophila gypsy insulator depends upon insulator anatomy and enhancer strength.

Insulators are specialized DNA sequences that prevent enhancer-activated transcription only when interposed between an enhancer and its target promoter. The Drosophila gypsy retrotransposon contains an insulator composed of 12 degenerate binding sites for the Suppressor of Hairy-wing [Su(Hw)] protei...

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Main Authors: Scott, K C, Taubman, A D, Geyer, P K
Formato: Artigo
Idioma:English
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1460797/
https://ncbi.nlm.nih.gov/pubmed/10511558
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1460797/
https://ncbi.nlm.nih.gov/pubmed/10511558