SPO14 separation-of-function mutations define unique roles for phospholipase D in secretion and cellular differentiation in Saccharomyces cerevisiae.

In Saccharomyces cerevisiae, phospholipase D (PLD), encoded by the SPO14 gene, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid. SPO14 is essential for cellular differentiation during meiosis and is required for Golgi function when the normal secretory apparat...

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Autores principales: Rudge, S A, Pettitt, T R, Zhou, C, Wakelam, M J, Engebrecht, J A
Formato: Artículo
Lenguaje:English
Publicado: 2001
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461740/
https://ncbi.nlm.nih.gov/pubmed/11514437
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1461740/
https://ncbi.nlm.nih.gov/pubmed/11514437

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