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Differential transplacental binding of valproic acid: influence of free fatty acids.

The unbound fraction of valproic acid (VPA) was found to be significantly lower in cord serum (6.0 +/- 0.8%) than in maternal serum collected before oxytocin (12.2 +/- 2.7%) or after delivery (9.9 +/- 2.3%). The difference was probably due to the concentration of free fatty acids (acting as displaci...

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Detalhes bibliográficos
Main Authors: Albani, F, Riva, R, Contin, M, Baruzzi, A, Altomare, M, Merlini, G P, Perucca, E
Formato: Artigo
Idioma:English
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463429/
https://ncbi.nlm.nih.gov/pubmed/6430314
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