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RNA aptamers selected against DNA polymerase β inhibit the polymerase activities of DNA polymerases β and κ
DNA polymerase β (polβ), a member of the X family of DNA polymerases, is the major polymerase in the base excision repair pathway. Using in vitro selection, we obtained RNA aptamers for polβ from a variable pool of 8 × 10(12) individual RNA sequences containing 30 random nucleotides. A total of 60 i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1463896/ https://ncbi.nlm.nih.gov/pubmed/16707660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl326 |
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