Induction of Multifunctional Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T Cells Capable of Proliferation in Healthy Subjects by Using a Prime-Boost Regimen of DNA- and Modified Vaccinia Virus Ankara-Vectored Vaccines Expressing HIV-1 Gag Coupled to CD8(+) T-Cell Epitopes

A double-blind randomized phase I trial was conducted in human immunodeficiency virus type 1 (HIV-1)-negative subjects receiving vaccines vectored by plasmid DNA and modified vaccinia virus Ankara (MVA) expressing HIV-1 p24/p17 gag linked to a string of CD8(+) T-cell epitopes. The trial had two grou...

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Main Authors: Goonetilleke, Nilu, Moore, Stephen, Dally, Len, Winstone, Nicola, Cebere, Inese, Mahmoud, Abdul, Pinheiro, Susana, Gillespie, Geraldine, Brown, Denise, Loach, Vanessa, Roberts, Joanna, Guimaraes-Walker, Ana, Hayes, Peter, Loughran, Kelley, Smith, Carole, De Bont, Jan, Verlinde, Carl, Vooijs, Danii, Schmidt, Claudia, Boaz, Mark, Gilmour, Jill, Fast, Pat, Dorrell, Lucy, Hanke, Tomas, McMichael, Andrew J.
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2006
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472051/
https://ncbi.nlm.nih.gov/pubmed/16641265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.10.4717-4728.2006
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC1472051/
https://ncbi.nlm.nih.gov/pubmed/16641265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.10.4717-4728.2006

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