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Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: Implications for 22q11 deletion syndrome

About 35% of patients with 22q11 deletion syndrome (22q11DS), which includes DiGeorge and velocardiofacial syndromes, develops psychiatric disorders, mainly schizophrenia and bipolar disorder. We previously reported that mice carrying a multigene deletion (Df1) that models 22q11DS have reduced prepu...

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Detalhes bibliográficos
Main Authors: Paylor, Richard, Glaser, Beate, Mupo, Annalisa, Ataliotis, Paris, Spencer, Corinne, Sobotka, Angela, Sparks, Chelsey, Choi, Chul-Hee, Oghalai, John, Curran, Sarah, Murphy, Kieran C., Monks, Stephen, Williams, Nigel, O’Donovan, Michael C., Owen, Michael J., Scambler, Peter J., Lindsay, Elizabeth
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472513/
https://ncbi.nlm.nih.gov/pubmed/16684884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600206103
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