Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus.

Antisense oligonucleotides complementary to specific mRNA sequences are widely used inhibitors of gene expression in vitro and in vivo . In vitro cationic lipids have been demonstrated to increase the pharmacological activity of antisense oligonucleotides by increasing cellular uptake and facilitati...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Marcusson, E G, Bhat, B, Manoharan, M, Bennett, C F, Dean, N M
Materyal Türü: Makale
Dil:en
Baskı/Yayın Bilgisi: 1998
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC147486/
https://ncbi.nlm.nih.gov/pubmed/9518498
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC147486/
https://ncbi.nlm.nih.gov/pubmed/9518498

Benzer Materyaller