Molecular chaperones of the Hsp110 family act as nucleotide exchange factors of Hsp70s

Hsp70 molecular chaperones function in protein folding in a manner dependent on regulation by co-chaperones. Hsp40s increase the low intrinsic ATPase activity of Hsp70, and nucleotide exchange factors (NEFs) remove ADP after ATP hydrolysis, enabling a new Hsp70 interaction cycle with non-native prot...

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Detalhes bibliográficos
Main Authors: Dragovic, Zdravko, Broadley, Sarah A, Shomura, Yasuhito, Bracher, Andreas, Hartl, F Ulrich
Formato: Artigo
Idioma:English
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1478182/
https://ncbi.nlm.nih.gov/pubmed/16688212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601138
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1478182/
https://ncbi.nlm.nih.gov/pubmed/16688212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601138

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