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Molecular Determinants of S-Glutathionylation of Carbonic Anhydrase 3

Carbonic anhydrase 3 is easily S-glutathionylated in vivo and in vitro. The protein has two surface-exposed cysteine residues that can be modified. We found that Cys186 is more readily glutathionylated than Cys181. We studied a series of site-specific mutants to identify the residues that interact w...

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Autors principals: KIM, GEUMSOO, LEVINE, RODNEY L.
Format: Article
Idioma:English
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578687/
https://ncbi.nlm.nih.gov/pubmed/15998239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2005.7.849
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