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Efficiency of carcinogenesis with and without a mutator mutation
Carcinogenesis involves the acquisition of multiple genetic changes altering various cellular phenotypes. These changes occur within the fixed time period of a human lifespan, and mechanisms that accelerate this process are more likely to result in clinical cancers. Mutator mutations decrease genome...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1599925/ https://ncbi.nlm.nih.gov/pubmed/16966602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606271103 |
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