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Why Molecular Chaperones Buffer Mutational Damage: A Case Study With a Yeast Hsp40/70 System
The malfunctioning of molecular chaperones may result in uncovering genetic variation. The molecular basis of this phenomenon remains largely unknown. Chaperones rescue proteins unfolded by environmental stresses and therefore they might also help to stabilize mutated proteins and thus mask damages....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
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Copyright © 2006 by the Genetics Society of America
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1602100/ https://ncbi.nlm.nih.gov/pubmed/16849597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.061564 |
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