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ADAMTS1 mediates the release of antiangiogenic polypeptides from TSP1 and 2

Matrix metalloproteases regulate both physiological and pathological events by processing matrix proteins and growth factors. ADAMTS1 in particular is required for normal ovulation and renal function and has been shown to modulate angiogenesis. Here we report that TSP1 and 2 are substrates of ADAMTS...

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Detalhes bibliográficos
Main Authors: Lee, Nathan V, Sato, Makoto, Annis, Douglas S, Loo, Joseph A, Wu, Lily, Mosher, Deane F, Iruela-Arispe, M Luisa
Formato: Artigo
Idioma:English
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636613/
https://ncbi.nlm.nih.gov/pubmed/17082774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601400
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