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The interplay of glycosylation and disulfide formation influences fibrillization in a prion protein fragment
It is now accepted that the structural transition from cellular prion protein (PrP(C)) to proteinase K-resistant prion protein scrapie (PrP(Sc)) is the major event leading to transmissible spongiform encephalopathies. Although the mechanism of this transition remains elusive, glycosylation has been...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado em: |
National Academy of Sciences
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164631/ https://ncbi.nlm.nih.gov/pubmed/12805563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232504100 |
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