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Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5α

Retroviral restriction factor TRIM5α exhibits a high degree of sequence variation among primate species. It has been proposed that this diversity is the cumulative result of ancient, lineage-specific episodes of positive selection. Here, we describe the contribution of within-species variation to th...

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Detalhes bibliográficos
Main Authors: Newman, Ruchi M., Hall, Laura, Connole, Michelle, Chen, Guo-Lin, Sato, Shuji, Yuste, Eloisa, Diehl, William, Hunter, Eric, Kaur, Amitinder, Miller, Gregory M., Johnson, Welkin E.
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679755/
https://ncbi.nlm.nih.gov/pubmed/17142324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605838103
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