Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus

A significant proportion of familial breast cancers cannot be explained by mutations in the BRCA1 or BRCA2 genes. We applied a strategy to identify predisposition loci for breast cancer by using mathematical models to identify early somatic genetic deletions in tumor tissues followed by targeted lin...

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Main Authors: Kainu, Tommi, Juo, Suh-Hang Hank, Desper, Richard, Schäffer, Alejandro A., Gillanders, Elizabeth, Rozenblum, Ester, Freas-Lutz, Diana, Weaver, Don, Stephan, Dietrich, Bailey-Wilson, Joan, Kallioniemi, Olli-P., Tirkkonen, Mika, Syrjäkoski, Kirsi, Kuukasjärvi, Tuula, Koivisto, Pasi, Karhu, Ritva, Holli, Kaija, Arason, Adalgeir, Johannesdottir, Gudrun, Bergthorsson, Jon Thor, Johannsdottir, Hrefna, Egilsson, Valgardur, Barkardottir, Rosa Björk, Johannsson, Oskar, Haraldsson, Karin, Sandberg, Therese, Holmberg, Eva, Grönberg, Henrik, Olsson, Håkan, Borg, Åke, Vehmanen, Paula, Eerola, Hannaleena, Heikkilä, Päivi, Pyrhönen, Seppo, Nevanlinna, Heli
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16911/
https://ncbi.nlm.nih.gov/pubmed/10944226
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC16911/
https://ncbi.nlm.nih.gov/pubmed/10944226

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