Intracellular Accumulation of Trehalose Protects Lactococcus lactis from Freeze-Drying Damage and Bile Toxicity and Increases Gastric Acid Resistance

Interleukin-10 (IL-10) is a promising candidate for the treatment of inflammatory bowel disease. Intragastric administration of Lactococcus lactis genetically modified to secrete IL-10 in situ in the intestine was shown to be effective in healing and preventing chronic colitis in mice. However, its...

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Detalhes bibliográficos
Main Authors: Termont, Sofie, Vandenbroucke, Klaas, Iserentant, Dirk, Neirynck, Sabine, Steidler, Lothar, Remaut, Erik, Rottiers, Pieter
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2006
Assuntos:
Physiology and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1694204/
https://ncbi.nlm.nih.gov/pubmed/17028239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01388-06
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1694204/
https://ncbi.nlm.nih.gov/pubmed/17028239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01388-06

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