Assessing the Genetic Diversity of the Aldolase Genes of Plasmodium falciparum and Plasmodium vivax and Its Potential Effect on Performance of Aldolase-Detecting Rapid Diagnostic Tests

Malaria-specific rapid diagnostic tests (RDTs) targeting aldolase show highly variable sensitivities. We assessed diversity in Plasmodium falciparum and P. vivax aldolases by sequencing the coding genes from parasites of various origins. The results show that aldolases are highly conserved, indicati...

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Bibliografiske detaljer
Main Authors: Lee, Nelson, Baker, Joanne, Bell, David, McCarthy, James, Cheng, Qin
Format: Artigo
Sprog:English
Udgivet: American Society for Microbiology 2006
Fag:
Parasitology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698405/
https://ncbi.nlm.nih.gov/pubmed/17021060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01611-06
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC1698405/
https://ncbi.nlm.nih.gov/pubmed/17021060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01611-06

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