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Peutz-Jeghers syndrome: confirmation of linkage to chromosome 19p13.3 and identification of a potential second locus, on 19q13.4.

Peutz-Jeghers syndrome (PJS) is an autosomal dominant disease with variable expression and incomplete penetrance, characterized by mucocutaneous pigmentation and hamartomatous polyposis. Patients with PJS have increased frequency of gastrointestinal and extraintestinal malignancies (ovaries, testes,...

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Detalhes bibliográficos
Main Authors: Mehenni, H, Blouin, J L, Radhakrishna, U, Bhardwaj, S S, Bhardwaj, K, Dixit, V B, Richards, K F, Bermejo-Fenoll, A, Leal, A S, Raval, R C, Antonarakis, S E
Formato: Artigo
Idioma:English
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716075/
https://ncbi.nlm.nih.gov/pubmed/9399902
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