Genetic variants of NHEJ DNA ligase IV can affect the risk of developing multiple myeloma, a tumour characterised by aberrant class switch recombination

The DNA double stranded break (DSB) repair mechanism, non-homologous end joining (NHEJ) represents an essential step in antigen receptor gene rearrangement mechanisms, processes believed to be intimately involved in the aetiology of lymphoproliferative disease. We investigated the potential impact t...

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Detalhes bibliográficos
Main Authors: Roddam, P, Rollinson, S, O'Driscoll, M, Jeggo, P, Jack, A, Morgan, G
Formato: Artigo
Idioma:English
Publicado em: BMJ Group 2002
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1757220/
https://ncbi.nlm.nih.gov/pubmed/12471202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.39.12.900
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1757220/
https://ncbi.nlm.nih.gov/pubmed/12471202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.39.12.900

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