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Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faecium.

Among its penicillin-binding proteins (PBPs), Enterococcus faecium possesses a low-affinity PBP5, PBP5fm, which is the main target involved in beta-lactam resistance. A 7.7-kb EcoRI chromosomal fragment of E. faecium D63r containing the pbp5fm gene was cloned and sequenced. Two open reading frames (...

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Main Authors:	Zorzi, W, Zhou, X Y, Dardenne, O, Lamotte, J, Raze, D, Pierre, J, Gutmann, L, Coyette, J, Tosques, I E, Shi, J, Shapleigh, J P, Wu, F, Wu, J, Ehley, J, Filutowicz, M, Climo, M W, Sharma, V K, Archer, G L, Barák, I, Youngman, P, Xie, Z D, Hershberger, C D, Shankar, S, Ye, R W, Chakrabarty, A M, Schurr, M J, Yu, H, Martinez-Salazar, J M, Boucher, J C, Deretic, V, Andersen, P S, Martinussen, J, Hammer, K, Kahler, A E, Switzer, R L, Moens, S, Schloter, M, Vanderleyden, J, Desai, P J, Angerer, A, Genco, C A, Atsumi, T, Maekawa, Y, Yamada, T, Kawagishi, I, Imae, Y, Homma, M, Welch, T J, Bartlett, D H, Qi, S Y, Moir, A, O'Connor, C D, Decatur, A, Losick, R, Rosche, W A, Jaworski, A, Kang, S, Kramer, S F, Larson, J E, Geidroc, D P, Wells, R D, Sinden, R R, Song, Y, Sargentini, N J, Heinzen, R A, Hackstadt, T, Dierksen, K P, Trempy, J E, Jarrell, K F, Bayley, D P, Kostyukova, A S, Ohno, T, Armand, S, Hata, T, Nikaidou, N, Henrissat, B, Mitsutomi, M, Watanabe, T, Kappes, R M, Kempf, B, Bremer, E, Huang, J, Cao, C, Lutkenhaus, J, Haijema, B J, Venema, G, Kooistra, J, Soncini, F C, García Véscovi, E, Solomon, F, Groisman, E A, Conter, A, Bouché, J P, Dassain, M, Taverna, P, Sedgwick, B, Fang, F C, Chen, C Y, Guiney, D G, Xu, Y, Boch, J, Schmid, R, Meima, R, Kloser, A W, Laird, M W, Misra, R, Liu, L, Nakano, M M, Lee, O H, Zuber, P, Hsing, W, Canale-Parola, E, Babitzke, P, Yealy, J, Campanelli, D, Christiansen, B, Brøndsted, L, Vogensen, F K, Elsen, S, Colbeau, A, Chabert, J, Vignais, P M, Gosink, K K, Gaal, T, Bokal, A J, Gourse, R L, McGee, K, Hörstedt, P, Milton, D L, Zhulin, I B, Bespalov, V A, Johnson, M S, Taylor, B L, Kelly, R F, Whitfield, C, Schweizer, H P, Po, C, Zhao, A C, Khan, S A, Peter, H, Burkovski, A, Krämer, R, Cordes, C, Twiest, B, Kazemier, B, van Dijl, J M, Bron, S, Motamedi, H, Shafiee, A, Cai, S J, Streicher, S L, Arison, B H, Miller, R R, Spence, E L, Kawamukai, M, Sanvoisin, J, Braven, H, Bugg, T D, Perfect, J R, Rude, T H, Wong, B, Flynn, T, Chaturvedi, V, Niehaus, W, Tavormina, P L, Landick, R, Gross, C A, Massidda, O, Kariyama, R, Daneo-Moore, L, Shockman, G D, Lang, S E, Jenney, F E, Daldal, F
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC178279/ https://ncbi.nlm.nih.gov/pubmed/8759860 https://ncbi.nlm.nih.gov/pmc/articles/PMC178280/ https://ncbi.nlm.nih.gov/pubmed/8759861 https://ncbi.nlm.nih.gov/pmc/articles/PMC178281/ https://ncbi.nlm.nih.gov/pubmed/8759862 https://ncbi.nlm.nih.gov/pmc/articles/PMC178282/ https://ncbi.nlm.nih.gov/pubmed/8759863 https://ncbi.nlm.nih.gov/pmc/articles/PMC178283/ https://ncbi.nlm.nih.gov/pubmed/8759864 https://ncbi.nlm.nih.gov/pmc/articles/PMC178284/ https://ncbi.nlm.nih.gov/pubmed/8759865 https://ncbi.nlm.nih.gov/pmc/articles/PMC178285/ https://ncbi.nlm.nih.gov/pubmed/8759866 https://ncbi.nlm.nih.gov/pmc/articles/PMC178286/ https://ncbi.nlm.nih.gov/pubmed/8759867 https://ncbi.nlm.nih.gov/pmc/articles/PMC178287/ https://ncbi.nlm.nih.gov/pubmed/8759868 https://ncbi.nlm.nih.gov/pmc/articles/PMC178288/ https://ncbi.nlm.nih.gov/pubmed/8759869 https://ncbi.nlm.nih.gov/pmc/articles/PMC178289/ https://ncbi.nlm.nih.gov/pubmed/8759870 https://ncbi.nlm.nih.gov/pmc/articles/PMC178290/ https://ncbi.nlm.nih.gov/pubmed/8759871 https://ncbi.nlm.nih.gov/pmc/articles/PMC178291/ https://ncbi.nlm.nih.gov/pubmed/8759872 https://ncbi.nlm.nih.gov/pmc/articles/PMC178292/ https://ncbi.nlm.nih.gov/pubmed/8759873 https://ncbi.nlm.nih.gov/pmc/articles/PMC178293/ https://ncbi.nlm.nih.gov/pubmed/8759874 https://ncbi.nlm.nih.gov/pmc/articles/PMC178294/ https://ncbi.nlm.nih.gov/pubmed/8759875 https://ncbi.nlm.nih.gov/pmc/articles/PMC178295/ https://ncbi.nlm.nih.gov/pubmed/8759876 https://ncbi.nlm.nih.gov/pmc/articles/PMC178296/ https://ncbi.nlm.nih.gov/pubmed/8759877 https://ncbi.nlm.nih.gov/pmc/articles/PMC178297/ https://ncbi.nlm.nih.gov/pubmed/8759878 https://ncbi.nlm.nih.gov/pmc/articles/PMC178298/ https://ncbi.nlm.nih.gov/pubmed/8752319 https://ncbi.nlm.nih.gov/pmc/articles/PMC178299/ https://ncbi.nlm.nih.gov/pubmed/8752320 https://ncbi.nlm.nih.gov/pmc/articles/PMC178300/ https://ncbi.nlm.nih.gov/pubmed/8752321 https://ncbi.nlm.nih.gov/pmc/articles/PMC178301/ https://ncbi.nlm.nih.gov/pubmed/8752322 https://ncbi.nlm.nih.gov/pmc/articles/PMC178302/ https://ncbi.nlm.nih.gov/pubmed/8752323 https://ncbi.nlm.nih.gov/pmc/articles/PMC178303/ https://ncbi.nlm.nih.gov/pubmed/8752324 https://ncbi.nlm.nih.gov/pmc/articles/PMC178304/ https://ncbi.nlm.nih.gov/pubmed/8752325 https://ncbi.nlm.nih.gov/pmc/articles/PMC178305/ https://ncbi.nlm.nih.gov/pubmed/8752326 https://ncbi.nlm.nih.gov/pmc/articles/PMC178306/ https://ncbi.nlm.nih.gov/pubmed/8752327 https://ncbi.nlm.nih.gov/pmc/articles/PMC178307/ https://ncbi.nlm.nih.gov/pubmed/8752328 https://ncbi.nlm.nih.gov/pmc/articles/PMC178308/ https://ncbi.nlm.nih.gov/pubmed/8752329 https://ncbi.nlm.nih.gov/pmc/articles/PMC178309/ https://ncbi.nlm.nih.gov/pubmed/8752330 https://ncbi.nlm.nih.gov/pmc/articles/PMC178310/ https://ncbi.nlm.nih.gov/pubmed/8752331 https://ncbi.nlm.nih.gov/pmc/articles/PMC178311/ https://ncbi.nlm.nih.gov/pubmed/8752332 https://ncbi.nlm.nih.gov/pmc/articles/PMC178312/ https://ncbi.nlm.nih.gov/pubmed/8752333 https://ncbi.nlm.nih.gov/pmc/articles/PMC178313/ https://ncbi.nlm.nih.gov/pubmed/8752334 https://ncbi.nlm.nih.gov/pmc/articles/PMC178314/ https://ncbi.nlm.nih.gov/pubmed/8752335 https://ncbi.nlm.nih.gov/pmc/articles/PMC178315/ https://ncbi.nlm.nih.gov/pubmed/8752336 https://ncbi.nlm.nih.gov/pmc/articles/PMC178316/ https://ncbi.nlm.nih.gov/pubmed/8752337 https://ncbi.nlm.nih.gov/pmc/articles/PMC178317/ https://ncbi.nlm.nih.gov/pubmed/8752338 https://ncbi.nlm.nih.gov/pmc/articles/PMC178318/ https://ncbi.nlm.nih.gov/pubmed/8752339 https://ncbi.nlm.nih.gov/pmc/articles/PMC178319/ https://ncbi.nlm.nih.gov/pubmed/8752340 https://ncbi.nlm.nih.gov/pmc/articles/PMC178320/ https://ncbi.nlm.nih.gov/pubmed/8752341 https://ncbi.nlm.nih.gov/pmc/articles/PMC178321/ https://ncbi.nlm.nih.gov/pubmed/8752342 https://ncbi.nlm.nih.gov/pmc/articles/PMC178322/ https://ncbi.nlm.nih.gov/pubmed/8752343 https://ncbi.nlm.nih.gov/pmc/articles/PMC178323/ https://ncbi.nlm.nih.gov/pubmed/8752344 https://ncbi.nlm.nih.gov/pmc/articles/PMC178324/ https://ncbi.nlm.nih.gov/pubmed/8752345 https://ncbi.nlm.nih.gov/pmc/articles/PMC178325/ https://ncbi.nlm.nih.gov/pubmed/8752346 https://ncbi.nlm.nih.gov/pmc/articles/PMC178326/ https://ncbi.nlm.nih.gov/pubmed/8752347 https://ncbi.nlm.nih.gov/pmc/articles/PMC178327/ https://ncbi.nlm.nih.gov/pubmed/8752348 https://ncbi.nlm.nih.gov/pmc/articles/PMC178328/ https://ncbi.nlm.nih.gov/pubmed/8752349
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Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faecium.

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