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PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization
Pleckstrin-2 is composed of 2 pleckstrin homology (PH) domains and a disheveled–Egl-10–pleckstrin (DEP) domain. A lipid-binding assay revealed that pleckstrin-2 binds with greatest affinity to D3 and D5 phosphoinositides. Pleckstrin-2 expressed in Jurkat T cells bound to the cellular membrane and en...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1785144/ https://ncbi.nlm.nih.gov/pubmed/17008542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-001339 |
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