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The shared epitope is a marker of severity associated with selection for, but not with response to, infliximab in a large rheumatoid arthritis population

OBJECTIVE: To determine whether joint destruction, indication for, and response to infliximab in rheumatoid arthritis are associated with the shared epitope (SE) or selected cytokine gene polymorphisms (interleukin (IL) 1B, IL1‐RN, and tumour necrosis α). METHODS: In a large rheumatoid arthritis pop...

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Detalhes bibliográficos
Main Authors: Marotte, H, Pallot‐Prades, B, Grange, L, Tebib, J, Gaudin, P, Alexandre, C, Blond, J L, Cazalis, M A, Mougin, B, Miossec, P
Formato: Artigo
Idioma:English
Publicado em: BMJ Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798045/
https://ncbi.nlm.nih.gov/pubmed/16096333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.037150
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