P-selectin glycoprotein ligand 1 therapy ameliorates established collagen-induced arthritis in DBA/1 mice partly through the suppression of tumour necrosis factor

We investigated the therapeutic potential of P-selectin glycoprotein ligand (PSGL)-1 in established collagen-induced arthritis (CIA) in DBA/1 mice. PSGL-1 is the high-affinity specific ligand for P-selectin and is thus important in cell recruitment to inflammatory sites. I-316 PSGL-1 or rPSGL-1Ig fu...

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Main Authors: SUMARIWALLA, P F, MALFAIT, A M, FELDMANN, M
Formato: Artigo
Idioma:English
Publicado em: Blackwell Science Inc 2004
Assuntos:
Animal Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808991/
https://ncbi.nlm.nih.gov/pubmed/15030516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02421.x
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1808991/
https://ncbi.nlm.nih.gov/pubmed/15030516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02421.x

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