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Agonistic antibodies to Fas induce a breach in the endothelial lining of the liver and a breakdown in B cell tolerance

Liver disease can be associated with a breakdown in self-tolerance and the production of autoantibodies such as rheumatoid factors (RF), which bind to IgG. Here we investigated whether primary, non-infectious liver damage was sufficient to induce autoantibody production. We established a model of ta...

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Detalhes bibliográficos
Main Authors: Newkirk, M M, Nowak, U, Skamene, E, Iera, D, Desbarats, J
Formato: Artigo
Idioma:English
Publicado em: Blackwell Science Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810459/
https://ncbi.nlm.nih.gov/pubmed/17223977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03279.x
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