The Fas pathway is involved in pancreatic β cell secretory function

Pancreatic β cell mass and function increase in conditions of enhanced insulin demand such as obesity. Failure to adapt leads to diabetes. The molecular mechanisms controlling this adaptive process are unclear. Fas is a death receptor involved in β cell apoptosis or proliferation, depending on the a...

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Detalhes bibliográficos
Main Authors: Schumann, Desiree M., Maedler, Kathrin, Franklin, Isobel, Konrad, Daniel, Størling, Joachim, Böni-Schnetzler, Marianne, Gjinovci, Asllan, Kurrer, Michael O., Gauthier, Benoit R., Bosco, Domenico, Andres, Axel, Berney, Thierry, Greter, Melanie, Becher, Burkhard, Chervonsky, Alexander V., Halban, Philippe A., Mandrup-Poulsen, Thomas, Wollheim, Claes B., Donath, Marc Y.
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1815272/
https://ncbi.nlm.nih.gov/pubmed/17299038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611487104
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1815272/
https://ncbi.nlm.nih.gov/pubmed/17299038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611487104

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