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The Fas pathway is involved in pancreatic β cell secretory function
Pancreatic β cell mass and function increase in conditions of enhanced insulin demand such as obesity. Failure to adapt leads to diabetes. The molecular mechanisms controlling this adaptive process are unclear. Fas is a death receptor involved in β cell apoptosis or proliferation, depending on the a...
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , |
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| Médium: | Článek |
| Jazyk: | English |
| Vydáno: |
National Academy of Sciences
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815272/ https://ncbi.nlm.nih.gov/pubmed/17299038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611487104 |
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