Purification and membrane reconstitution of catalytically active Menkes copper-transporting P-type ATPase (MNK; ATP7A)

The MNK (Menkes disease protein; ATP7A) is a major copper- transporting P-type ATPase involved in the delivery of copper to cuproenzymes in the secretory pathway and the efflux of excess copper from extrahepatic tissues. Mutations in the MNK (ATP7A) gene result in Menkes disease, a fatal neurodegene...

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Main Authors: Hung, Ya Hui, Layton, Meredith J., Voskoboinik, Ilia, Mercer, Julian F. B., Camakaris, James
Formato: Artigo
Idioma:English
Publicado em: Portland Press Ltd. 2006
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820817/
https://ncbi.nlm.nih.gov/pubmed/17009961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060924
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1820817/
https://ncbi.nlm.nih.gov/pubmed/17009961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060924

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