Alimentary tract innervation deficits and dysfunction in mice lacking GDNF family receptor α2

Subsets of parasympathetic and enteric neurons require neurturin signaling via glial cell line–derived neurotrophic factor family receptor α2 (GFRα2) for development and target innervation. Why GFRα2-deficient (Gfra2(–/–)) mice grow poorly has remained unclear. Here, we analyzed several factors that...

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Detalhes bibliográficos
Main Authors: Rossi, Jari, Herzig, Karl-Heinz, Võikar, Vootele, Hiltunen, Päivi H., Segerstråle, Mikael, Airaksinen, Matti S.
Formato: Artigo
Idioma:en
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC182204/
https://ncbi.nlm.nih.gov/pubmed/12952919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317995
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https://ncbi.nlm.nih.gov/pmc/articles/PMC182204/
https://ncbi.nlm.nih.gov/pubmed/12952919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317995

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