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Therapeutic activity of enviroxime against rhinovirus infection in volunteers.

The therapeutic effect of intranasal 2-amino-1-(isopropylsulphonyl)-6-benzimidazole phenyl ketone oxime (enviroxime) against human rhinovirus type 9 was evaluated in a double-blind, placebo-controlled volunteer trial. Enviroxime given 6 times a day was well tolerated, producing a reduction in clinic...

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Detalhes bibliográficos
Main Authors:	Phillpotts, R J, Wallace, J, Tyrrell, D A, Tagart, V B, Smee, D F, Martin, J C, Verheyden, J P, Matthews, T R, Schwenzer, K S, Anhalt, J P, Cable, D, Overturf, G, Edralin, G, Foulds, G, Stankewich, J P, Marshall, D C, O'Brien, M M, Hayes, S L, Weidler, D J, McMahon, F G, Caporaso, N, Smith, S M, Eng, R H, DiPiro, J T, Taylor, A T, Steele, J C, Kenady, D E, Ram, M D, Magera, B E, Arroyo, J C, Rosansky, S J, Postic, B, Babiuk, L A, Acres, S D, Misra, V, Stockdale, P H, De Clercq, E, Mattila, J, Männistö, P T, Mäntylä, R, Nykänen, S, Lamminsivu, U, Marsh, P K, Malamy, M H, Shimell, M J, Tally, F P, Yan, R T, Chen, J S, Eron, L J, Park, C H, Hixon, D L, Goldenberg, R I, Poretz, D M, Wiencek, K M, Klapes, N A, Foegeding, P M, Biggs, W H, Wunderlich, A C, Corbeil, L C, Davis, C E, Curd, J G, Nakamura, S, Nakata, K, Katae, H, Minami, A, Kashimoto, S, Yamagishi, J, Takase, Y, Shimizu, M, van de Guchte, M, Kodde, J, van der Vossen, J M, Kok, J, Venema, G, McDowell, T D, Buchanan, C E, Coyette, J, Swavely, T S, Shockman, G D, Nies, Loring, Vogel, Timothy M., Selitrennikoff, C P, Snarski, Virginia M., Lundell, Taina, Leonowicz, Andrzej, Rogalski, Jerzy, Hatakka, Annele, Chirife, J, Herszage, L, Joseph, A, Kohn, E S, Kuhn, Elmar P., Townsend, G. Todd, Suflita, Joseph M., Schell, Ronald F., Smith, Bruce R., Lefrock, Jack L., Francisco, Maryalice, Rubinstein, A, Lee, C Y, Bhatnagar, L, Saha, B C, Lee, Y E, Takagi, M, Imanaka, T, Bagdasarian, M, Zeikus, J G, Pollock, Helen M., Holt, Jean, Murray, Cecilia, Wüst, Jürg, Hardegger, Ursula, Kaneko, Tsutomu, Takahashi, Masahiro, Suzuki, Hideki, Ginsburg, C M, McCracken, G H, Olsen, K, Sterling, R P, Connor, D J, Norman, J C, Cooley, D A, Sivonen, K, Carmichael, W W, Namikoshi, M, Rinehart, K L, Dahlem, A M, Niemelä, S I, Bourgault, Anne-Marie, Gauvreau, Léo, Michel, J, Rogol, M, Dickman, D, Stoner, D. L., Wey, J. E., Barrett, K. B., Jolley, J. G., Wright, R. B., Dugan, P. R., Lüthi, E, Jasmat, N B, Bergquist, P L, Venkatadri, Rajagopalan, Irvine, Robert L., Schmidt, S. K., Gier, M. J., Bhat, Siva, Wallace, R. J., Ørskov, E. R., Doyle, Cathy J., Hirst, Mark L., Cory, Jenny S., Entwistle, Philip F., Kamau, D N, Doores, S, Pruitt, K M, Sánchez-Amat, A., Torrella, F., Leenhouts, Kees J., Kok, Jan, Venema, Gerard, Keister, Donald L., Marsh, Sarah S., Kadokura, H, Yoda, K, Imai, M, Yamasaki, M, Romeyer, F M, Jacobs, F A, Brousseau, R, Zolg, J W, Lanciotti, R S, Wendlinger, M, Meyer, W A
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	1983
Assuntos:	Research Article Applied Environmental and Public Health Microbiology General Microbial Ecology Physiology and Biotechnology Susceptibility Mechanisms of Resistance Food Microbiology Mycology Microorganism-Plant Interactions Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC184785/ https://ncbi.nlm.nih.gov/pubmed/6870216 https://ncbi.nlm.nih.gov/pmc/articles/PMC184786/ https://ncbi.nlm.nih.gov/pubmed/6307132 https://ncbi.nlm.nih.gov/pmc/articles/PMC184787/ https://ncbi.nlm.nih.gov/pubmed/6347058 https://ncbi.nlm.nih.gov/pmc/articles/PMC184788/ https://ncbi.nlm.nih.gov/pubmed/6223578 https://ncbi.nlm.nih.gov/pmc/articles/PMC184789/ https://ncbi.nlm.nih.gov/pubmed/6307133 https://ncbi.nlm.nih.gov/pmc/articles/PMC184790/ https://ncbi.nlm.nih.gov/pubmed/6870217 https://ncbi.nlm.nih.gov/pmc/articles/PMC184791/ https://ncbi.nlm.nih.gov/pubmed/6870218 https://ncbi.nlm.nih.gov/pmc/articles/PMC184792/ https://ncbi.nlm.nih.gov/pubmed/6870219 https://ncbi.nlm.nih.gov/pmc/articles/PMC184793/ https://ncbi.nlm.nih.gov/pubmed/6870220 https://ncbi.nlm.nih.gov/pmc/articles/PMC184794/ https://ncbi.nlm.nih.gov/pubmed/6307134 https://ncbi.nlm.nih.gov/pmc/articles/PMC184797/ https://ncbi.nlm.nih.gov/pubmed/6870221 https://ncbi.nlm.nih.gov/pmc/articles/PMC184800/ https://ncbi.nlm.nih.gov/pubmed/6870222 https://ncbi.nlm.nih.gov/pmc/articles/PMC184801/ https://ncbi.nlm.nih.gov/pubmed/2275527 https://ncbi.nlm.nih.gov/pmc/articles/PMC184802/ https://ncbi.nlm.nih.gov/pubmed/6307135 https://ncbi.nlm.nih.gov/pmc/articles/PMC184803/ https://ncbi.nlm.nih.gov/pubmed/2275528 https://ncbi.nlm.nih.gov/pmc/articles/PMC184804/ https://ncbi.nlm.nih.gov/pubmed/6603195 https://ncbi.nlm.nih.gov/pmc/articles/PMC184805/ https://ncbi.nlm.nih.gov/pubmed/6223579 https://ncbi.nlm.nih.gov/pmc/articles/PMC184806/ https://ncbi.nlm.nih.gov/pubmed/2125811 https://ncbi.nlm.nih.gov/pmc/articles/PMC184807/ https://ncbi.nlm.nih.gov/pubmed/6191654 https://ncbi.nlm.nih.gov/pmc/articles/PMC184808/ https://ncbi.nlm.nih.gov/pubmed/16348270 https://ncbi.nlm.nih.gov/pmc/articles/PMC184809/ https://ncbi.nlm.nih.gov/pubmed/6223580 https://ncbi.nlm.nih.gov/pmc/articles/PMC184810/ https://ncbi.nlm.nih.gov/pubmed/16348271 https://ncbi.nlm.nih.gov/pmc/articles/PMC184811/ https://ncbi.nlm.nih.gov/pubmed/16348272 https://ncbi.nlm.nih.gov/pmc/articles/PMC184812/ https://ncbi.nlm.nih.gov/pubmed/6870223 https://ncbi.nlm.nih.gov/pmc/articles/PMC184813/ https://ncbi.nlm.nih.gov/pubmed/16348273 https://ncbi.nlm.nih.gov/pmc/articles/PMC184814/ https://ncbi.nlm.nih.gov/pubmed/6307136 https://ncbi.nlm.nih.gov/pmc/articles/PMC184815/ https://ncbi.nlm.nih.gov/pubmed/6870224 https://ncbi.nlm.nih.gov/pmc/articles/PMC184816/ https://ncbi.nlm.nih.gov/pubmed/2125812 https://ncbi.nlm.nih.gov/pmc/articles/PMC184817/ https://ncbi.nlm.nih.gov/pubmed/6307137 https://ncbi.nlm.nih.gov/pmc/articles/PMC184818/ https://ncbi.nlm.nih.gov/pubmed/6870225 https://ncbi.nlm.nih.gov/pmc/articles/PMC184819/ https://ncbi.nlm.nih.gov/pubmed/16348274 https://ncbi.nlm.nih.gov/pmc/articles/PMC184820/ https://ncbi.nlm.nih.gov/pubmed/6307138 https://ncbi.nlm.nih.gov/pmc/articles/PMC184821/ https://ncbi.nlm.nih.gov/pubmed/6870226 https://ncbi.nlm.nih.gov/pmc/articles/PMC184822/ https://ncbi.nlm.nih.gov/pubmed/2125813 https://ncbi.nlm.nih.gov/pmc/articles/PMC184823/ https://ncbi.nlm.nih.gov/pubmed/6870227 https://ncbi.nlm.nih.gov/pmc/articles/PMC184824/ https://ncbi.nlm.nih.gov/pubmed/6870228 https://ncbi.nlm.nih.gov/pmc/articles/PMC184825/ https://ncbi.nlm.nih.gov/pubmed/2125814 https://ncbi.nlm.nih.gov/pmc/articles/PMC184826/ https://ncbi.nlm.nih.gov/pubmed/16348275 https://ncbi.nlm.nih.gov/pmc/articles/PMC184827/ https://ncbi.nlm.nih.gov/pubmed/2275529 https://ncbi.nlm.nih.gov/pmc/articles/PMC184828/ https://ncbi.nlm.nih.gov/pubmed/16348276 https://ncbi.nlm.nih.gov/pmc/articles/PMC184829/ https://ncbi.nlm.nih.gov/pubmed/16348277 https://ncbi.nlm.nih.gov/pmc/articles/PMC184830/ https://ncbi.nlm.nih.gov/pubmed/16348278 https://ncbi.nlm.nih.gov/pmc/articles/PMC184831/ https://ncbi.nlm.nih.gov/pubmed/16348279 https://ncbi.nlm.nih.gov/pmc/articles/PMC184832/ https://ncbi.nlm.nih.gov/pubmed/2125815 https://ncbi.nlm.nih.gov/pmc/articles/PMC184833/ https://ncbi.nlm.nih.gov/pubmed/16348280 https://ncbi.nlm.nih.gov/pmc/articles/PMC184834/ https://ncbi.nlm.nih.gov/pubmed/16348281 https://ncbi.nlm.nih.gov/pmc/articles/PMC184835/ https://ncbi.nlm.nih.gov/pubmed/16348282 https://ncbi.nlm.nih.gov/pmc/articles/PMC184836/ https://ncbi.nlm.nih.gov/pubmed/2275530 https://ncbi.nlm.nih.gov/pmc/articles/PMC184837/ https://ncbi.nlm.nih.gov/pubmed/2148862 https://ncbi.nlm.nih.gov/pmc/articles/PMC184838/ https://ncbi.nlm.nih.gov/pubmed/2275531
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Therapeutic activity of enviroxime against rhinovirus infection in volunteers.

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