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Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans
Expansion of polyglutamine repeats in several unrelated proteins causes neurodegenerative diseases with distinct but related pathologies. To provide a model system for investigating common pathogenic features, we have examined the behavior of polyglutamine expansions expressed in Caenorhabditis eleg...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado em: |
The National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC18505/ https://ncbi.nlm.nih.gov/pubmed/10811890 |
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