Caveolin-1/3 Double-Knockout Mice Are Viable, but Lack Both Muscle and Non-Muscle Caveolae, and Develop a Severe Cardiomyopathic Phenotype

The caveolin gene family consists of caveolins 1, 2, and 3. Caveolins 1 and 2 are co-expressed in many cell types, such as endothelial cells, fibroblasts, smooth muscle cells and adipocytes, where they form a heteroligomeric complex. In contrast, the expression of caveolin-3 is muscle-specific. Thus...

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Main Authors: Park, David S., Woodman, Scott E., Schubert, William, Cohen, Alex W., Frank, Philippe G., Chandra, Madhulika, Shirani, Jamshid, Razani, Babak, Tang, Baiyu, Jelicks, Linda A., Factor, Stephen M., Weiss, Louis M., Tanowitz, Herbert B., Lisanti, Michael P.
Formato: Artigo
Idioma:English
Publicado em: American Society for Investigative Pathology 2002
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Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850810/
https://ncbi.nlm.nih.gov/pubmed/12057923
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1850810/
https://ncbi.nlm.nih.gov/pubmed/12057923

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