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Composite synthetic lethal identification of membrane traffic inhibitors

Small molecule inhibitors provide powerful tools to characterize highly dynamic and complex eukaryotic cell pathways such as those mediating membrane traffic. However, a lack of easy and generalizable assays has constrained identification of novel inhibitors despite availability of diverse chemical...

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Detalhes bibliográficos
Main Authors: Duncan, Mara C., Ho, David G., Huang, Jing, Jung, Michael E., Payne, Gregory S.
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851079/
https://ncbi.nlm.nih.gov/pubmed/17404221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607773104
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