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Growth inhibitory properties of endothelin-1 in human hepatic myofibroblastic Ito cells. An endothelin B receptor-mediated pathway.

Ito cells play a pivotal role in the development of liver fibrosis associated with chronic liver diseases. During this process, Ito cells acquire myofibroblastic features, proliferate, and synthesize fibrosis components. Considering the reported mitogenic properties of endothelin-1 (ET-1), we invest...

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Detalhes bibliográficos
Main Authors: Mallat, A, Fouassier, L, Préaux, A M, Gal, C S, Raufaste, D, Rosenbaum, J, Dhumeaux, D, Jouneaux, C, Mavier, P, Lotersztajn, S
Formato: Artigo
Idioma:en
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC185171/
https://ncbi.nlm.nih.gov/pubmed/7615814
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