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Sequence variation in human succinate dehydrogenase genes: evidence for long-term balancing selection on SDHA

BACKGROUND: Balancing selection operating for long evolutionary periods at a locus is characterized by the maintenance of distinct alleles because of a heterozygote or rare-allele advantage. The loci under balancing selection are distinguished by their unusually high polymorphism levels. In this rep...

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Detalhes bibliográficos
Main Authors: Baysal, Bora E, Lawrence, Elizabeth C, Ferrell, Robert E
Formato: Artigo
Idioma:English
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852088/
https://ncbi.nlm.nih.gov/pubmed/17376234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-5-12
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