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Poly(d,l-Lactide-Coglycolide) Particles Containing Gentamicin: Pharmacokinetics and Pharmacodynamics in Brucella melitensis- Infected Mice

Drug delivery systems containing gentamicin were studied as a treatment against experimental brucellosis in mice. Micro- and nanoparticles prepared by using poly(d,l-lactide-coglycolide) (PLGA) 502H and microparticles made of PLGA 75:25H were successfully delivered to the liver and the spleen, the t...

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Detalhes bibliográficos
Main Authors: Lecaroz, M. C., Blanco-Prieto, M. J., Campanero, M. A., Salman, H., Gamazo, C.
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855454/
https://ncbi.nlm.nih.gov/pubmed/17220415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00809-06
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