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Effects of population structure on genetic association studies

Population-based case-control association is a promising approach for unravelling the genetic basis of complex diseases. One potential problem of this approach is the presence of population structure in the samples. Using the Collaborative Study on the Genetics of Alcoholism (COGA) single-nucleotide...

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Detalhes bibliográficos
Main Authors: Xu, Hongyan, Shete, Sanjay
Formato: Artigo
Idioma:English
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866830/
https://ncbi.nlm.nih.gov/pubmed/16451565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S109
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