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Presenilin Binding Protein Is Associated with Neurofibrillary Alterations in Alzheimer’s Disease and Stimulates Tau Phosphorylation

A novel presenilin binding protein, PBP, has recently been identified. PBP is localized to the particulate fraction of extracts of Alzheimer’s disease brain but is found in the soluble fractions of brain from age matched normal controls. It is shown here that PBP is associated with neurofibrillary t...

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Auteurs principaux: Chen, Qi, Yoshida, Hirotaka, Schubert, David, Maher, Pamela, Mallory, Margaret, Masliah, Eliezer
Format: Article
Langue:English
Publié: American Society for Investigative Pathology 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867048/
https://ncbi.nlm.nih.gov/pubmed/11696419
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