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Hypothalamic resistin induces hepatic insulin resistance

Circulating resistin stimulates endogenous glucose production (GP). Here, we report that bi-directional changes in hypothalamic resistin action have dramatic effects on GP and proinflammatory cytokine expression in the liver. The infusion of either resistin or an active cysteine mutant in the third...

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Detalhes bibliográficos
Main Authors: Muse, Evan D., Lam, Tony K.T., Scherer, Philipp E., Rossetti, Luciano
Formato: Artigo
Idioma:English
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868785/
https://ncbi.nlm.nih.gov/pubmed/17525801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30440
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