Mutations in the N Termini of Herpes Simplex Virus Type 1 and 2 gDs Alter Functional Interactions with the Entry/Fusion Receptors HVEM, Nectin-2, and 3-O-Sulfated Heparan Sulfate but Not with Nectin-1

Multiple cell surface molecules (herpesvirus entry mediator [HVEM], nectin-1, nectin-2, and 3-O-sulfated heparan sulfate) can serve as entry receptors for herpes simplex virus type 1 (HSV-1) or HSV-2 and also as receptors for virus-induced cell fusion. Viral glycoprotein D (gD) is the ligand for the...

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Main Authors: Yoon, Miri, Zago, Anna, Shukla, Deepak, Spear, Patricia G.
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187404/
https://ncbi.nlm.nih.gov/pubmed/12915538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9221-9231.2003
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https://ncbi.nlm.nih.gov/pmc/articles/PMC187404/
https://ncbi.nlm.nih.gov/pubmed/12915538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9221-9231.2003

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