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Beyond the 3′ end: experimental validation of extended transcript isoforms

High throughput EST and full-length cDNA sequencing have revealed extensive variations at the 3′ ends of mammalian transcripts. Whether all of these changes are biologically meaningful has been the subject of controversy, as such, results may reflect in part transcription or polyadenylation leakage....

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Detalhes bibliográficos
Main Authors: Moucadel, Virginie, Lopez, Fabrice, Ara, Takeshi, Benech, Philippe, Gautheret, Daniel
Formato: Artigo
Idioma:English
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874610/
https://ncbi.nlm.nih.gov/pubmed/17339231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm062
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