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Weight related differences in the pharmacokinetics of abacavir in HIV-infected patients

AIM: To study the possible influence of patient characteristics on abacavir pharmacokinetics. METHODS: A population pharmacokinetic model for abacavir was developed using data from 188 adult patients by the use of a nonlinear mixed effects modelling method performed with NONMEM. RESULTS: Abacavir ph...

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Detalhes bibliográficos
Main Authors: Jullien, V, Tréluyer, J-M, Chappuy, H, Dimet, J, Rey, E, Dupin, N, Salmon, D, Pons, G, Urien, S
Formato: Artigo
Idioma:English
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884744/
https://ncbi.nlm.nih.gov/pubmed/15676040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02259.x
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