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Association between CYP1A2 activity and riluzole clearance in patients with amyotrophic lateral sclerosis
AIMS: Riluzole is used in a fixed dosing schedule of 50 mg twice daily to treat patients with amyotropic lateral sclerosis (ALS), one form of motor neurone disease. The large variability in the pharmacokinetics of riluzole may be a factor contributing to its limited therapeutic benefit. Riluzole is...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Blackwell Science Inc
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884790/ https://ncbi.nlm.nih.gov/pubmed/15752377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02233.x |
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