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Two E2 binding sites alone are sufficient to function as the minimal origin of replication of human papillomavirus type 18 DNA.

Replication of papillomaviruses requires an origin of replication and two virus-encoded proteins, E1 and E2. Using a transient replication assay for human papillomavirus type 18 (HPV-18) DNA, we have found that two adjacent sequences present within the origin of replication can independently support...

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Detalhes bibliográficos
Main Authors: Sverdrup, F, Khan, S A
Formato: Artigo
Idioma:en
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188713/
https://ncbi.nlm.nih.gov/pubmed/7815514
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