Recombinant adeno-associated virus mediates a high level of gene transfer but less efficient integration in the K562 human hematopoietic cell line.

We tested the ability of a recombinant adeno-associated virus (rAAV) vector to express and integrate exogenous DNA into human hematopoietic cells in the absence of selection. We developed an rAAV vector, AAV-tNGFR, carrying a truncated rat nerve growth factor receptor (tNGFR) cDNA as a cell surface...

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Detalhes bibliográficos
Main Authors: Malik, P, McQuiston, S A, Yu, X J, Pepper, K A, Krall, W J, Podsakoff, G M, Kurtzman, G J, Kohn, D B
Formato: Artigo
Idioma:en
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC191246/
https://ncbi.nlm.nih.gov/pubmed/9032306
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC191246/
https://ncbi.nlm.nih.gov/pubmed/9032306

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