Mass Spectrometry-Based Systems Approach for Identification of Inhibitors of Plasmodium falciparum Fatty Acid Synthase

The emergence of strains of Plasmodium falciparum resistant to the commonly used antimalarials warrants the development of new antimalarial agents. The discovery of type II fatty acid synthase (FAS) in Plasmodium distinct from the FAS in its human host (type I FAS) opened up new avenues for the deve...

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Detalhes bibliográficos
Main Authors: Sharma, Shilpi, Sharma, Shailendra Kumar, Modak, Rahul, Karmodiya, Krishanpal, Surolia, Namita, Surolia, Avadhesha
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology (ASM) 2007
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Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913259/
https://ncbi.nlm.nih.gov/pubmed/17485508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00124-07
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1913259/
https://ncbi.nlm.nih.gov/pubmed/17485508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00124-07

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