Affected-sib-pair analyses reveal support of prior evidence for a susceptibility locus for bipolar disorder, on 21q.

In 22 multiplex pedigrees screened for linkage to bipolar disorder, by use of 18 markers on chromosome 21q, single-locus affected-sib-pair (ASP) analysis detected a high proportion (57%-62%) of alleles shared identical by descent (IBD), with P values of .049-.0008 on nine marker loci. Multilocus ASP...

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Main Authors: Detera-Wadleigh, S. D., Badner, J. A., Goldin, L. R., Berrettini, W. H., Sanders, A. R., Rollins, D. Y., Turner, G., Moses, T., Haerian, H., Muniec, D., Nurnberger, J. I., Gershon, E. S.
Formato: Artigo
Idioma:English
Publicado em: 1996
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1915054/
https://ncbi.nlm.nih.gov/pubmed/8651306
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1915054/
https://ncbi.nlm.nih.gov/pubmed/8651306

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