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DNA Damage Responses in Neural Cells: Focus on the Telomere

Postmitotic neurons must survive for the entire life of the organism and be able to respond adaptively to adverse conditions of oxidative and genotoxic stress. Unrepaired DNA damage can trigger apoptosis of neurons which is typically mediated by the ataxia telangiectasia mutated (ATM) - p53 pathway....

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Detalhes bibliográficos
Main Authors: Zhang, Peisu, Dilley, Carolyn, Mattson, Mark P.
Formato: Artigo
Idioma:English
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924472/
https://ncbi.nlm.nih.gov/pubmed/17207936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2006.11.052
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