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Insertion Sequence 1515 in the ply Gene of a Type 1 Clinical Isolate of Streptococcus pneumoniae Abolishes Pneumolysin Expression

A serotype 1 Streptococcus pneumoniae strain isolated by blood culture from a woman with pneumonia was found to harbor insertion sequence (IS) 1515 in the pneumolysin gene, abolishing pneumolysin expression. To our knowledge, this is the first report of an IS in the pneumolysin gene of S. pneumoniae...

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Detalhes bibliográficos
Main Authors: Garnier, Fabien, Janapatla, Rajendra Prasad, Charpentier, Emmanuelle, Masson, Geoffrey, Grélaud, Carole, Stach, Jean François, Denis, François, Ploy, Marie-Cécile
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933007/
https://ncbi.nlm.nih.gov/pubmed/17494718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02168-06
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