A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases

Hybrid polar compounds (HPCs) have been synthesized that induce terminal differentiation and/or apoptosis in various transformed cells. We have previously reported on the development of the second-generation HPCs suberoylanilide hydroxamic acid (SAHA) and m-carboxycinnamic acid bishydroxamide (CBHA)...

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Bibliografiske detaljer
Main Authors: Richon, Victoria M., Emiliani, Stephane, Verdin, Eric, Webb, Yael, Breslow, Ronald, Rifkind, Richard A., Marks, Paul A.
Format: Artigo
Sprog:en
Udgivet: The National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19684/
https://ncbi.nlm.nih.gov/pubmed/9501205
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC19684/
https://ncbi.nlm.nih.gov/pubmed/9501205

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