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A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases

Hybrid polar compounds (HPCs) have been synthesized that induce terminal differentiation and/or apoptosis in various transformed cells. We have previously reported on the development of the second-generation HPCs suberoylanilide hydroxamic acid (SAHA) and m-carboxycinnamic acid bishydroxamide (CBHA)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Richon, Victoria M., Emiliani, Stephane, Verdin, Eric, Webb, Yael, Breslow, Ronald, Rifkind, Richard A., Marks, Paul A.
Formatua: Artikulua
Hizkuntza:en
Argitaratua: The National Academy of Sciences 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC19684/
https://ncbi.nlm.nih.gov/pubmed/9501205
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